Approaches for the Labeling of Peptides with Tc-99m
نویسندگان
چکیده
منابع مشابه
Sentinel node detection failure due to defective labeling and large particle size of Tc-99m antimony sulfide colloid
Introduction: Many radiotracers have been used for sentinel node mapping with acceptable results. The main difference between these radiotracers is the particle size. In the current study, we reported defective labeling of Tc-99m antimony sulfide colloid which resulted in large particle size. Methods: Tc-99m-Antimony sulfide colloid was used for axillary sentinel n...
متن کاملThe labeling of platelet with Tc-99m and In-111 [Persian]
We separated platelets from whole blood and incorporated them into In-Ill and Te-99m agents. Sn-GHA, Tropolone, Oxine (sulphate) and HMPAO were used to diffuse radionuclides into the platelets. The effects of time, temperature, PH of incubation media; volume and concentration of ionophore; and volume and activity of ln-l 13m C13 and Te-99m on labeling efficiency were studied.
متن کاملAn improved synthesis and preliminary biodistribution study of a Technetium-99m-labeled 2-amino-2-deoxy(thioacetyl)-D-glucose complex ([99mTc]-TA-DG) as a tumor imaging agent
Introduction: This report describes the synthesis of 2-Amino-2-deoxy(S-benzoylthioacetyl)-D-glucose (S-Bz-TA-DG), radiolabeled with [99mTc(CO)3(OH2)3]+ complex with a procedure including deprotection of the benzoyl group, characterization by HPLC using a C18 reverse phase column and preliminary biodistribution study in normal ...
متن کاملOptimization condition in labeling of Ofloxacin with 99mTc and its biological evaluation in Staphylococcus aureus and Escherichia coli for infection imaging
Introduction: The use of radiopharmaceuticals is a powerful tool in the management of patients with infectious or inflammatory diseases in nuclear medicine. In this study ofloxacin as a second-generation fluoroquinolone is used to design a desired infection imaging agent after labeling with 99mTc via direct labeling. Methods: Ofloxacin was radiolabeled with 99mTc using di...
متن کاملClinical significance of additional lateral imaging in diagnosis of prosthesis infection by combined Tc-99m labeled leukocyte/bone marrow scintigraphy
Introduction: Recently the most accurate diagnostic method in the diagnosis of prosthesis infection is the combination of Tc-99m labeled leukocyte/bone marrow imaging. However the diagnostic efficiency of the test is influenced because of its low spatial resolution. Recently SPECT/CT imaging is implicated in this test with efficient additional diagnostic improvement. In the dep...
متن کامل